Ramirez is on the roster of Triple-A Salt Lake. The suspension, announced Thursday, will begin at the start of the Bees' season.
Ramirez, who will turn 26 in March, served a 50-game suspension for his second offense at the start of last season. Playing for Double-A Arkansas, he batted .206 with six homers and 22 RBIs in 48 games.
There were 60 suspensions last year under the minor league drug program and 15 under the major league program.